Please Read the attached Word Document for complete instruction. you can also find some example poster i attached for your reference as well. bellow is a summary of the project .
Purpose: To acquaint the student with methods for prediction of proteinfunction and structure. To familiarize the student with basic bioinformaticstools and databases.
Assignment: You will be given a GenBank ID. From that you will findthe amino acid sequence. Don’t be confused. Focus your attention on thisprotein, not the organism from which it comes. Proteins are selected thathave the annotation “unkown function,” so you might not be able to find thefunction nor be able to figure out a likely function. Perform a search forhomologs. Maybe one of the homologues will have a known function. Thefunction of a homologue provides you with a possible function for yourprotein, but evolution might have caused the function to change. Print out acomparison of the proteins. Indicate regions of relatively high identity,functional motifs, and potential post-translational modification sites. Give anoverall assessment of the possible function of your protein in the organism.If it is an enzyme, give the biochemical reaction that the protein is primarilyresponsible for and your predicted biological outcome if a loss-of-functionmutation occurs in the gene that codes for the protein.You may also be able to get information about your gene if you analyze thesynteny of the gene that produces your protein. In addition, give thepredictions of structure and disorder, and the predicted secondary andtertiary structures of the protein (note: a region predicted to be disorderedcan also have predicted secondary structure). Note also that disorderedregions are sometimes observed to have gain of function mutations, such asthe gain of a PTM site or the gain of a partner binding site.
Format: The above information will be organized into a poster such as onegiven at a scientific meeting. During the indicated time period, you willpresent your poster orally. You will have 12 minutes for your presentation,so you should practice your presentation with someone else. The time limitswill be strictly enforced.
Making Your Poster: You can use “How to create a poster with PowerPoint” on YouTube to learn how to make your poster using PowerPoint.This ~ 10-minute tutorial will provide you with the basics to enable you tocreate an excellent poster.https://www.youtube.com/watch?v=1c9Kd_mUFDM